Amitriptyline Tablets

Amitriptyline Tablets


AMITRIPTYLINE (a mee TRIP ti leen) is used to treat depression.

This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions.

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How should I use this medicine?

Take this medicine by mouth with a drink of water. Follow the directions on the prescription label. You can take the tablets with or without food. Take your medicine at regular intervals. Do not take it more often than directed. Do not stop taking this medicine suddenly except upon the advice of your doctor. Stopping this medicine too quickly may cause serious side effects or your condition may worsen.
A special MedGuide will be given to you by the pharmacist with each prescription and refill. Be sure to read this information carefully each time.

Talk to your pediatrician regarding the use of this medicine in children. Special care may be needed.

Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once.

NOTE: This medicine is only for you. Do not share this medicine with others.

What if I miss a dose?

If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.

What should I tell my health care provider before I take this medicine?
They need to know if you have any of these conditions:

An alcohol problem
Asthma, difficulty breathing
Bipolar disorder or schizophrenia
Difficulty passing urine, prostate trouble
Heart disease or previous heart attack
Liver disease
Over active thyroid
Thoughts or plans of suicide, a previous suicide attempt, or family history of suicide attempt
An unusual or allergic reaction to amitriptyline, other medicines, foods, dyes, or preservatives
Pregnant or trying to get pregnant

What may interact with this medicine?

Do not take this medicine with any of the following medications:

Arsenic trioxide
Certain medicines used to regulate abnormal heartbeat or to treat other heart conditions
MAOIs like Carbex, Eldepryl, Marplan, Nardil, and Parnate
Methylene blue
Other medicines for mental depression
Phenothiazines like perphenazine, thioridazine and chlorpromazine
St. John’s Wort
This medicine may also interact with the following medications:

Atropine and related drugs like hyoscyamine, scopolamine, tolterodine and others
Barbiturate medicines for inducing sleep or treating seizures, like phenobarbital
Thyroid hormones such as levothyroxine
This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.

What side effects may I notice from receiving this medicine?

Side effects that you should report to your doctor or health care professional as soon as possible

Allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue
Abnormal production of milk in females
Breast enlargement in both males and females
Breathing problems
Confusion, hallucinations
Fast, irregular heartbeat
Fever with increased sweating
Muscle stiffness, or spasms
Pain or difficulty passing urine, loss of bladder control
Suicidal thoughts or other mood changes
Swelling of the testicles
Tingling, pain, or numbness in the feet or hands
Yellowing of the eyes or skin
Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):

Change in sex drive or performance
Constipation or diarrhea
Nausea, vomiting
Weight gain or loss
This list may not describe all possible side effects. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What should I watch for while using this medicine?

Tell your doctor if your symptoms do not get better or if they get worse. Visit your doctor or health care professional for regular checks on your progress. Because it may take several weeks to see the full effects of this medicine, it is important to continue your treatment as prescribed by your doctor.

Patients and their families should watch out for new or worsening thoughts of suicide or depression. Also watch out for sudden changes in feelings such as feeling anxious, agitated, panicky, irritable, hostile, aggressive, impulsive, severely restless, overly excited and hyperactive, or not being able to sleep. If this happens, especially at the beginning of treatment or after a change in dose, call your health care professional.

You may get drowsy or dizzy. Do not drive, use machinery, or do anything that needs mental alertness until you know how this medicine affects you. Do not stand or sit up quickly, especially if you are an older patient. This reduces the risk of dizzy or fainting spells. Alcohol may interfere with the effect of this medicine. Avoid alcoholic drinks.

Do not treat yourself for coughs, colds, or allergies without asking your doctor or health care professional for advice. Some ingredients can increase possible side effects.

Your mouth may get dry. Chewing sugarless gum or sucking hard candy, and drinking plenty of water will help. Contact your doctor if the problem does not go away or is severe.

This medicine may cause dry eyes and blurred vision. If you wear contact lenses you may feel some discomfort. Lubricating drops may help. See your eye doctor if the problem does not go away or is severe.

This medicine can cause constipation. Try to have a bowel movement at least every 2 to 3 days. If you do not have a bowel movement for 3 days, call your doctor or health care professional.

This medicine can make you more sensitive to the sun. Keep out of the sun. If you cannot avoid being in the sun, wear protective clothing and use sunscreen. Do not use sun lamps or tanning beds/booths.

Where should I keep my medicine?

Keep out of the reach of children.

Store at room temperature between 20 and 25 degrees C (68 and 77 degrees F). Throw away any unused medicine after the expiration date.

Where should I keep my medicine?
Keep out of the reach of children.

Store at room temperature between 20 and 25 degrees C (68 and 77 degrees F). Throw away any unused medicine after the expiration date.

Additional Information


10 mg (12 tablets), 25 mg (10 tablets), 50 mg (10 tablets), 75 mg (30 tablets), 100 mg (30 tablets), 150 mg (100 tablets)